Saperavi is the most widespread Georgian red grape variety, which can be found in every vineyard of the Kakheti winemaking region as well as in almost all other regions of Georgia. Saperavi grapes can also be found abroad. Some scientists(e.g. D. Tabidze) believe that western Georgia was birthplace of Saperavi and that it spread from there to Kartli and Kakheti via southern Georgia. Saperavi grapes ripen during the second half of September, but are not harvested until the second half of October. High-quality red dry wines with great potential for ageing are produced from Saperavi grapes. Saperavi grapes are also used in the productions of sweet, semi-sweet, and rose wines. Some of the best wine is produced from Saperavi grapes picked in Mukuzani-Akhasheni, Khashmi, Kindzmarauli, Napareuli, Kvareli and Kondoli.

Krakhuna is an Imeretian variety of white grape, which tends to ripen late, and from which some of the strongest and most full-bodied Imeretian white wines are produced. Wines produced from Krakhuna grapes have a high alcoholic content, are straw colored with tints of golden sunlight, and have aromas of ripe fruit (apricot or banana, for example) and honey. This wine has great potential foe ageing, and indeed becomes deeper and more interesting after a few years. The best micro-zones for Krakhuna are villages of Sviri, Obcha and Dimi.

Kisi is indigenous to Kakheti. It ripens before Rkatsiteli, typically in the last 2 weeks of September, and is made both in the European and Georgian manner. Occasionally it is fortified. A straw-coloured wine when produced in the European style, the nose is quite floral with flavours of pear, citrus and green tea on the palate; the amber Qvevri wines reveal more apricot, mango, lime, orange and walnut character. Some Producers believe it to be capable of producing finer, more expressive wines than Rkatsiteli. Kisi is also grown in Kartli.

The Variety grows widely in eastern Georgia, especially in Kakheti where it originated. It is recommended for higher-altitude, cooler mountain plantings along with Mtsvane Kakhuri. Khikhvi is relatively versatile, as it can be produced in light dry, semi-sweet, sweet, and, as in PDO Kardenakhi, fortified styles. Its aromatic signature is distinctive: floral notes of boxwood and wild flowers heighten broader flavours of ripe yellow fruits and apricot. The light wines appear both in European and Qvevri versions, the latter wines accentuate the dried fruit and flower character. With moderate alcohol levels and soft acidity, Kikhvi may stand alone as single varietal wine, or may contribute high-tones to enhance a blend.